Pogba's red card against Arsenal on Saturday has been accepted by Manchester United, meaning the £90 million midfielder is ruled out of Sunday's crucial Premier League derby and will instead take the field in the club's final Champions League group game.
Mourinho said he will not risk the 29-year-old for the match, with United requiring a point to secure top spot in Group A.
The surprise defeat to Basel last time out was a disappointment but United have done enough in their previous four games to put themselves in a position where they should still progress as group winners.
The Sun says Mourinho will have an £80m United transfer war-chest in January, it is understood.
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"He sometimes needs some very hard work on the muscular area which supports [the] knee which had problems". And when the period for that hard work comes, also the fatigue comes.
The powerful midfielder will however, play no part on Match Day 6.
"He's on that cycle of work now, divided between gym and pitch". He'll be out again tomorrow [Tuesday], but back to normal work after CSKA.
The left-back has been a peripheral figure at Old Trafford this season having managed a total of 48 minutes as a substitute over two appearances in the League Cup against Burton and Swansea.
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Newcastle were at one time linked to the 22-year-old Shaw but his £20m price tag is said to have deterred the Magpies, whereas Darmian's more modest asking price of £15m has already attracted interest from Sevilla and Roma. "More importantly, the others deserve an opportunity to play".
"Selected for Tuesday, yes for sure". For me I can not just pick one. Ahead of the tie, Jose Mourinho iterated that he will make a few changes to his side, by resting a few regulars.
"I would think that Mourinho will play a more cautious game".
Marouane Fellaini, Eric Bailly and Phil Jones are all still out for United, while Zlatan Ibrahimovic will not feature as Mourinho treads carefully with the Swede following a lengthy absence. "He plays tomorrow", Mourinho said. "It's the next match, the match that matters. But he's very happy to play and to try to keep his momentum because since he was back from injury, he's been phenomenal".
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