In addition to the feeling that you have just put a live coal in your mouth, you may weep, vomit and wonder where in your life you took a wrong turn.
Eating the world's hottest chilli left a 34-year-old man in hospital with excruciating headaches and neck pain. "He waited for a few days but kept on getting a headache again and again, so he came to the ER".
RCVS is characterised by temporary artery narrowing often accompanied by a thunderclap headache.
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"Given the development of symptoms immediately after exposure to a known vasoactive substance [substances that cause constriction of blood vessels], it is plausible that our patient had RCVS secondary to the Carolina Reaper", the authors wrote. A bird's eye chilli - small and hot enough for most spice-lovers - contains up to 225,000.
So what exactly happened to the man who ate the hot pepper?
And his had slightly high blood pressure of 134/69mm Hg.
The Carolina Reaper, which supermarket giant Tesco stocked last summer, is so hot that people are supposed to wear gloves when they handle it.
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The railway department has formed a team of senior officers to investigate the incident. There have been numerous such instances of train engines travelling on their own.
The Reaper was bred to reach record levels of heat.
In comparison, a Jalapeno pepper typically rates between 2,500 to 5,000 units on the scale - around 400 times less than a Carolina Reaper.
In November 2016, a new record of 120 grammes (just over four ounces) of Carolina Reaper were eaten in one minute at a competition in Arizona. But Smokin Ed, as he calls himself, also gave the impression that was not such a bad thing.
"This is the first time that pepper has been related to RCVS", Gunasekaran said.
As readers who have had the dubious pleasure of watching combative cooking-themed television shows such as Man v. Food already know, sometimes the simple act of eating can take on an unpleasant aspect of machismo and challenge. He has a partnership with a company that produces them.
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