He got the opener midway through the first half and then netted a superb second four minutes after the break.
He has led Atletico into their new stadium and to the club's third Europa League triumph in nine years, while also keeping them on course to finish above Real in La Liga.
"Griezmann today confirmed what he has been doing year by year".
"He was decisive in the most important moment in the game". He's played three finals with us and won two.
Torres fulfils childhood dream in Europa League final
Previously known as the UEFA Cup, it's format was changed and became known as the UEFA Europa League during the 2009/2010 campaign.
"We're talking to the club to see what can be done".
Griezmann, who was named man of the match in Lyon, has been Atletico's leading scorer in each season since he joined from Real Sociedad for £23.7m in July 2014.
"If he decides that he does not want to continue with us, we have to respect his decision".
Buffon to walk away from Italy again
Gianluigi Buffon admitted he fears retirement as the veteran Juventus captain looks set to make an announcement about his future. Buffon has spent his illustrious career in Italy, having swapped boyhood club Parma for Juventus in 2001.
"We hoped that he'd be at 100 per cent and we gave him a fitness test this morning. If he stays we'll keep growing because we are destined to keep growing".
It is Griezmann's first major title as an Atletico player, and a fitting way to bow out if he leaves at the end of the season with Barcelona tipped as his next destination.
"It made me especially odd to play against Antoine (Griezmann) and, decidedly, every time I play against him, I do not win".
Stan Lee files 1 Billion USD lawsuit against former company POW! Entertainment
When he had first formed POW!, it was meant to be a mere holding company for his vast property used for comics and animation. Grant of Alpert, Barr & Grant, seeks to rescind the license agreement as well as "damages in excess of one billion dollars".
Dozens of arrests were made across France and for the most part in Marseille, following football fans' fierce clashes after the final whistle sounded in a Europa League match late Wednesday.
Marseille was going for a second European trophy, 25 years after winning the Champions League, but had no answer to Griezmann's mobility and finishing.
Lucas Glover's wife faces domestic violence charge after golfer's poor round
The incident report shows Lucas told deputies Krista gets violent every time he doesn't play well in a major PGA tournament. According to Lucas Glover , three times PGA Tour victor , this is the reality every time he messes up on the golf course.