The Duke of Cambridge said the initiative's mission was to create a "big shift in working culture" and ensure that dealing with mental health is a part of everyday working life. It's really tough work as an air ambulance and search and rescue pilot.
During the event, the duke will also meet representatives from a number of organisations who have shown leadership in promoting good mental health in their own workplaces.
Prince William has confessed he "took a lot home without realising" when he worked as an air ambulance pilot.
The Duke of Cambridge, 36, shared the revelation while speaking at the launch of Mental Health at Work, a UK-based initiative that helps support mental health causes in the workplace.
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He said Lloyds would be making "substantial use" of the Mental Health at Work gateway, which he described as a "hugely impressive undertaking".
William added: "If you see sad things every day, you think all life is like that, you're just seeing all the sad things, all the pain every day".
'That you're always dealing with despair, sadness, injury, things that are really quite troubling.
"As employers, we have a real opportunity to change the way we approach mental health, giving our people the support they need to thrive".
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It found nearly half of the 44,000 workers questioned had experienced poor mental health in their current job.
The survey of more than 44,000 employees also revealed that only half of those who had experienced poor mental health had talked to their employer about it, suggesting that as many as one in four United Kingdom workers is struggling in silence.
The project Wwebsite, as part of the Royal Foundation's Heads Together campaign and the mental health charity Mind, will provide resources, training and information for managers who struggle to find the help.
During his visit to Bristol, William met people already benefiting from the online gateway.
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Kevin Miller, a 50-year-old electrician, said he planned to ride out the storm at his home near Charleston . North and SC and Virginia declared emergencies earlier in the week.
Prince William opened up about his own struggles with mental health reminding everyone that despite the "blue blood" he was born with, he is still human.